Accelerating ASO treatments from progression to application

.Completing rate of interests.R.S., M.S., H.G. and also A.A.R. are coordinators of the 1M1M project.

H.G. and also A.A.R. are actually board of supervisors participants and also R.S., M.S.

and A.A.R. are members of the clinical consultatory committee of N1C. A.A.R.

makes known job by LUMC, which has licenses on exon-skipping innovation, several of which has actually been accredited to BioMarin and also subsequently sublicensed to Sarepta. As co-inventor of a few of these patents, A.A.R. was actually entitled to a portion of aristocracies.

A.A.R. even more makes known working as impromptu specialist for PTC Therapies, Sarepta Rehabs, Regenxbio, Dyne Therapeutics, Lilly, BioMarin Pharmaceuticals Inc., Eisai, Entrada, Takeda, Splicesense, Galapagos, Sapreme, Italfarmaco and Astra Zeneca. Before 5 years, A.A.R.

additionally executed impromptu consulting for Alpha Anomeric. A.A.R. additionally states registration of the medical boards of advisers of Eisai, Hybridize Rehabs, Silence Therapeutics, Sarepta Therapeutics, Sapreme and Mitorx.

In the past 5 years, A.A.R. was actually likewise a medical advisory board member for ProQR. Wage for A.A.R.

u00e2 s consulting as well as recommending activities is paid out to LUMC. In the past 5 years, LUMC also got audio speaker honoraria from PTC Therapeutics, Alnylam Netherlands, Italfarmaco as well as Pfizer and also moneying for arrangement study coming from Sapreme, Eisai, Galapagos, Synaffix and also Alpha Anomeric. Venture backing is acquired from Sarepta Therapies as well as Entrada via unrestricted grants.

H.G. possesses absolutely nothing to make known relative to the subjects dealt with in this manuscript. Over the last 5 years, he has additionally obtained consultancy gratuity from UCB.

M.S. obtained working as a consultant gratuity from Ionis, UCB, Prevail, Orphazyme, Biogen, Servier, Reata, GenOrph, AviadoBio, Biohaven, Zevra, Lilly as well as Solaxa previously 5 years, all unconnected to the here and now manuscript. R.S.

possesses nothing at all to make known relative to the subject matters dealt with in this particular document. She has actually obtained speaker and/or consultancy honoraria or even financing payments coming from Abbvie, Bial, STADA as well as Everpharma before 5 years.